A NEW DIRECTION IN THE DEVELOPMENT OF A VETERINARY DRUG OF THE SINBIOTIC TYPE

DOI: https://doi.org/10.29296/25877313-2021-07-05
Issue: 
7
Year: 
2021

N.A. Zasypkina Master, MIREA - Russian Technological University (Moscow, Russia) A.V. Aydakova Post-graduate Student, MIREA - Russian Technological University; Deputy General Director, SYNAPSE LLC (Moscow, Russia) E-mail: ann.reznikova2012@ya.ru A.V. Chumak bachelor, MIREA - Russian Technological University (Moscow, Russia) D.O. Shatalov Ph.D. (Pharm.), Associate Professor, MIREA - Russian Technological University (Moscow); General Director SYNAPSE LLC (Moscow, Russia) N.A. Mikhailova Dr.Sc. (Med.), Professor, Deputy Director for Research, I. Mechnikov Research Institute of Vaccines and Sera (Moscow, Russia) A.I. Gromakova Dr.Sc. (Pharm.), Chief Research Scientist, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow, Russia) A.P. Kaplun Dr.Sc. (Chem.), Professor, MIREA - Russian Technological University (Moscow, Russia) V.N. Davydova Dr.Sc. (Pharm.), Chief Research Scientist, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow, Russia)

Often, medicinal and feed antibiotics are actively used in the diet of cattle, which improve metabolism and increase the immunity of the animal, and in addition, allow for a longer time to ensure the safety of feed. However, concerns about the development of antimicrobial resistance led to the introduction of a ban on the use of antibiotics as growth stimulants, which led to the search for alternative methods to control and prevent pathogenic bacterial colonization. In recent years, it is probiotics that have begun to gain popularity as an alternative to antibiotics. In agriculture, the most popular are probiotics based on bacteria of the genus Bacillus, which are able to withstand both high and low temperatures, fluctuating pH values, produce many different enzymes (lipases, hydrolases and others), antibiotics, vitamins, proteins, are stable during storage, environmentally friendly and technologically advanced in production. Recently, a promising direction is the creation of an effective veterinary drug enriched with processed forest biomass (green trees, branches and bark, stem wood waste). Due to the inclusion of such a non-standard additive in the feed, physiological processes in the body of animals are normalized, appetite increases, their growth, productivity improves, and the body's immunity increases. Thus, it is promising to combine probiotic supplements and prebiotics, since the manifestation of a synergistic effect of these supplements is expected. This will increase the overall productivity potential of cattle, improve the quality of feed and reduce the price of feed additives.

Keywords: 
Bacillus subtilis
coniferous energy supplement
synbiotics
veterinary medicine
feed production

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