THE CHEMICAL INVESTIGATION THE SALVIA OFFICINALIS L. ROOTS. TRITERPENOIDS

Issue: 
12
Year: 
2015

M.K. Bulusheva
Post-graduate Student,
All-Russian Scientific Research Institute of Medical and Aromatic Plants (VILAR), Moscow
A.A. Savina
Ph. D. (Chem.), Leading Research Scientist,
All-Russian Scientific Research Institute of Medical and Aromatic Plants (VILAR), Moscow
V.I. Sheichenko
Ph.D. (Phys.-Math.), Leading Research Scientist,
All-Russian Scientific Research Institute of Medical and Aromatic Plants (VILAR), Moscow
S.V. Goryainov
Head of the Laboratory of Mass-Spectrometry and NMR Spectroscopy, Peoples' Friendship University of Russia, Moscow
T.A. Sokol´skaya
Dr.Sc. (Pharm.), Professor,
All-Russian Scientific Research Institute of Medical and Aromatic Plants (VILAR), Moscow
O.F. Lasskaya
Research Scientist, All-Russian Scientific Research Institute of Medical and Aromatic Plants (VILAR), Moscow
N.S. Tropina
Post-graduate Student, All-Russian Scientific Research Institute of Medical and Aromatic Plants (VILAR), Moscow

In our previous study we confirmed Royleanones of Salvia officinalis roots, the compounds having antibacterial activity. Horminone – is an API 50% by weight of a antimicrobial preparation developed in our laboratory. There was compared the antibacterial activity of each Royleanones. The most active is horminone. In this study we have isolated and identified some other components being extracted from salvia officinalis roots along with royleanone horminone. Salvia officinalis roots were harvested in Krasnodar region near Vasyurinskaya village. Ethanol extract was evaporated and treated with water- chloroform mixture, and then the resulting chloroform extract – with water solution of alkali. The precipitate obtained by adding acid solution wa separated by means of SG column chromatography, petroleum ether – chloroform and chloroform – methanol mixtures being used as eluents. The compounds isolated are oleanolic, ursolic, euscaphic and 19-desoxyeuscaphic acids identified by their 1H NMR and mass spectral data.

Keywords: 
Key words: Salvia officinalis roots
triterpenoids.