STUDY OF THE CHEMICAL COMPOSITION OF THE AERIAL PARTS OF PLANTAGO MAXIMA BY GAS CHROMATOGRAPHY MASS SPECTROMETRY
Issue:
6
Year:
2016
Last decades demonstrated an increased interest to the search of novel phytochemical drugs characterized by combination of
high efficiency and low toxicity, that is especially important in treatment of chronic diseases or prolonged rehabilitation process. Plantago
L. based compositions are widely used in traditional and folk medicine. Plantago maxima Juss. ex Jacq. that is not included into
the State Pharmacopoeia of the Russian Federation is growing in Orenburg region and its preparations are used as anti-inflammatory and antibacterial agents. Earlier the authors have studied certain therapeutic properties of P. maxima leaves. The aim of the current
study was analysis of biologically active substances content in leaves of Plantago maxima Juss. ex Jacq. collected in South Ural region.
The analyzed substances were measured using standard spectrophotometric methods and gas chromatography mass spectrometry.
The obtained results demonstrate that P. maxima leaves contain a complex of biologically active substances. In detail, the leaves contain
3,85±0,08 mg/100g of iridoids, 6,84±0,11 mg/100g of tannides, 3,25±0,04 mg/100g of flavonoids, 63,68±0,19 mg/100g of
ascorbic acid, 5,01±0,18 mg/100 g of tocopherol, 23,07±0,25 mg/100g of carotenoids. The method of gas chromatography mass
spectrometry allows to determine tocopherol, phytol, squalene, sitosterol, Methyl-7-methylcyclopenta [c] pyran-4-carboxylate,
3-[3-Bromophenyl]-7-chloro-3,4-dihydro-10-hydroxy-1,9(2H,10H)-acridinedione in the raw materials (leaves) of Plantago maxima
Juss. ex Jacq.
Keywords:
Key words: medicinal plants
plantain
Plantago maxima
biologically active substances
GCMS.