SURFACE ENERGY AND WETTABILITY OF SOLID POLYMER FILMS IN MODELING OF PROPERTIES OF EMBOLI FOR BLOCKAGE OF THE BLOOD VESSELS

Issue: 
5
Year: 
2017

О.А. Legonkova Dr.Sc. (Eng.), Head of Department, Institute of Surgery named after A.V. Vishnevsky (Moscow) E-mail: ospolimed@mail.ru , V.S. Stepanenko Ph.D. (Chem.), Research Scientist, Institute of Physical Chemistry and Electro-Chemistry named after A.N. Frumkina (Moscow), E.S. Zhavoronok Ph.D. (Chem.), Associate Professor, Moscow Technological Institute, L.Ju. Asanova Junior Research Scientist, Institute of Surgery named after A.V. Vishnevsky (Moscow), M.S. Belova Ph.D. (Biol.), Research Scientist, Institute of Surgery named after A.V. Vishnevsky (Moscow), A.V. Panov Ph.D. (Chem.), Research Scientist, Institute of Physical Chemistry and Electro-Chemistry named after A.N. Frumkina (Moscow), I.P. Savchenkova Dr.Sc. (Biol.), Head of Laboratory, All-Russian Institute on Experimental Veterinary named after Ja.R. Kovalenko (Moscow), A.E. Chalykh Dr.Sc. (Chem.), Head of Laboratory, Institute of Physical Chemistry and Electro-Chemistry named after A.N. Frumkina (Moscow)

The wettability and the surface energy of solid polymer samples, which is the basis for emboli occlusion of blood vessels from solutions in situ were studied. It was shown that the surface energy of the samples, as well as its disperse and polar parts varied slightly when exposed into aqueous environment. It was found that the polymer embolus have to be well wetted by blood components but the surface energy is slightly lower than the surface energy of the culture of multipotent mesenchymal stromal cells, similar to the tissue of vascular walls.

Keywords: 
Key words: blood vessel
embolization
polymer solution
embolus
surface energy
wettability
cytotoxicity.