PARTICULARITIES OF THE RELATIONSHIPS OF PHYTO-CHEMICAL COMPOSITION OF ANTIDIABETIC MEDICINAL PLANTS WITH THEIR THERAPEUTIC PROPERTIES

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Issue: 
5
Year: 
2017

M.U. Sharofova Ph.D. (Med.), Director of the Institute of Avicenna’s Medicine and Pharmacology (Dushanbe, Republic of Tajikistan) E-mail: mijgona72@mail.ru, Yu.N. Nuraliev Dr.Sc. (Med), Professor, Head of Pharmacology Department CSRL, Avicenna’s Tajik State Medical University (Dushanbe, Republic of Tajikistan) E-mail: usuf-nurali@mail.ru, Sh.S. Sagdieva Ph.D. (Med.),Head of theDepartment of Valeology and Physical Training Avicenna’s TSMU (Dushanbe, Republic of Tajikistan) E-mail: shoistass@mail.ru

The problem of widespread diabetes worldwide becomes more urgent task of modern medicine, given the number of hidden cas-es, multiple complications and comorbidities, with subsequent disability, which greatly increases the mortality from this disease. Effec-tive diabetes treatment should include natural sugar-reducing and metabolism-correcting means that have a broad spectrum of thera-peutic action and is more similar with nature of the human body, they gently remove metabolic imbalance and maintain normal blood sugar levels. In the opposite of synthetic sugar-reducing agents, medicinal plants carefully affect the activity of internal organs, nervous sys-tem and the vascular bed. Long-term use of herbal medicine can save successful treatment of diabetes, due to the large arsenal of anti-diabetic medicinal plants, which should be administered to patients considering their «mizadzh» (nature) both short-term and long-term courses, changing them depending on the degree of effectiveness of herbal remedies. In the article the advantages of herbal antidiabetic drugs compared with synthetic, based on the features of the spectrum of ther-apeutic properties, biochemical composition, toxicity and their impact on co-morbiditiesare analyzed. Our studies have confirmed that the most common biologically active substances with antidiabetic properties are polyphenols and flavonoids. They are contained in the composition of many medicinal plants of Tajikistan, vegetables, fruits, wild and cultivated berries. Research reported in this publication was supported by the Fogarty International Center of the National Institutes of Health un-der Award Number D43TW009672. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Keywords: 
Key words: diabetes
medicinal plants
anti-diabetic properties
phytotherapy.

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