THE MODELING OF THE REACTION OF ALKALINE HYDROLYSIS ACETYLGORMINON AT THE STAGE OF THE LIQUID PHASE EXTRACTION OF OBTAINING SUBSTANCE OF ANTIMICROBIAL ACTION FROM SALVIA OFFICINALIS L. ROOTS

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Issue: 
8
Year: 
2017

M.K. Bulusheva Post-graduate Student, Research Scientist, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow) E-mail: mbulusheva@inbox.ru,

V.I. Sheichenko Ph.D. (Phys.-Math.), Leading Research Scientist, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow),

A.A. Savina Ph.D. (Chem.) Leading Research Scientist, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow)

The roots of Salvia officinalis contains basically two compounds having antimicrobial activity: 7-hydroxyroyleanon (horminone) and 7-acetoxyroyleanon (acetoxyhorminone). To prove the possibility of obtaining an antimicrobial action substance by alkaline treatment of the royleanones sum with recieving horminone, there was modeled the reaction of alkaline hydrolysis of acetylhorminone. As a result of the described experiments modeling the reaction of hydrolysis of acetylhorminone and the ability of the horminone to remain stable for 24 hours, the possibility of using this reaction in the technology of obtaining the substance of the antimicrobial action of Roilevin is shown.

Keywords: 
Salvia officinalis roots
horminone
acetoxyhorminone’s alkaline hydrolysis
stability of horminone in an alkaline medium.

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