PRELIMINARY SCREENING AND COMPARATIVE STUDY OF XANTHIUM STRUMARIUM ANTIOXIDATIVE ACTIVITY IN VITRO

Issue: 
11
Year: 
2017

G.R. Bushueva
Ph.D. (Pharm.), Leading Research Scientist, Phytochemie Department,
All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow)
I.A. Lupanova
Ph.D. (Biol.), Deputy of the Head of the Center of Medicine,
All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow)

There is much information about the presence of antioxidant potential in plants of the Asteraceae family in the scientific literature due to the content of such secondary metabolites as phenols, flavonoids and tannins in them. Most plants belonging to the family Asteraceae contain chemical compounds with antibacterial, antitumor and antioxidant properties. In this respect, a poorly studied weakly poisonous plant common cocklebur (Xanthium strumarium L.), which draws the attention of researchers from different countries in connection with a diverse pharmacological action, is of particular interest. It is known that extracts from cocklebur have antifungal, anti-inflammatory, antitrypansosomal, hypoglycemic, antihelminthic, antiulcer, diuretic and anti-cancer activities. The purpose of this work is to study the adaptogenic, antioxidant and antimicrobial activity of aquatic and aquatic-alcohol extracts of common cocklebur (Xanthium strumarium L.) using glutathione reductase and catalase specific enzyme biotest-systems under in vitro conditions. Samples for the study were obtained by extracting the herb cocklebur of 24% ordinary, 40% and 70% ethanol and water. As a result of the studies, it was found that 24 and 40% alcohol extracts of cocklebur cocklebur do have an expressed antioxidant properties.

Keywords: 
common cocklebur
Xanthium strumarium
antioxidant activity
enzymatic biotest systems
catalase
glutathione reductase.