COMPARATIVE STUDY OF THE COMPONENT COMPOSITION OF ESSENTIAL OIL ARTEMISIA SPLENDENS WILLD. AND ARTEMISIA TSCHERNIEVIANA BESS. FLORA OF DAGESTAN

DOI: https://doi.org/10.29296/25877313-2018-01-04
Download full text PDF
Issue: 
1
Year: 
2018

F.A. Vagabova Ph.D.(Eng.), Senior Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Scientific Center of RAS (Makhachkala) Е-mail: fazina@mail.ru A.M. Aliev Senior Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Scientific Center of RAS (Makhachkala); Senior Research Scientist institute of physic, Dagestan Scientific Center of RAS (Makhachkala) Е-mail: aslan4848@yahoo.com G.K. Radjabov Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Scientific Center of RAS (Makhachkala) Е-mail: chem.@mail.ru A.M. Musaeva Head of Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Scientific Center of RAS (Makhachkala) Е-mail: musaev-58@lust.ru

For the first time, the total content and chemical composition of the essential oil Artemisia splendens Willd and Artemisia tschernieviana Bess were studiedfrom natural populations of the flora of Dagestan. Comparative characteristics of the component composition of essential oil of two Dagestan species of the genus Artemisia L. is given. In Dagestan, the genus of Artemisia L. is represented by 21 species. Samples Artemisia tschernieviana Bess. аnd Artemisia splendens Willd. for analysis were collected in natural populations of Dagestan at an altitude of 60 and 580 m above sea level in the flowering phase of 2014 and 2013, respectively. The extraction of essential oil from the samples was carried out by hydrodistillation, the component composition of the resulting oil by chromatography-mass spectrometry. The yield of essential oil was 0.23% and 0.88% for A. splendens and A. tschernieviana. In A. splendens essential oil, 26 compounds were found, 12 of which have concentra-tions above 1%, and the main compounds are artemisia-ketone (27.20%), longiriverbone (37.56%), trans-sabinyl acetate (10.40% %). The major component composition of the essential oil of the A. splendens aerial part of the Dagestan sample is very different from that of the well-known sample collected in Iran (1,8-cineole, caryophyllene oxide, valensen, and α-terpinyl-acetate). In the essential oil of the Dagestan A. tschernieviana sample 51 components were found, 15 of them have a concentration above 1%, and the main ones are α-pinene (8.90%), β-pinene (10.69%), limonene (9.10%), α-bisabolol (35.14%). It should be noted that some monoterpenes (pinenes, limonene), characteristic for the studied Iranian samples, are present in the essential oil of the aboveground part of A. tschernieviana of the Dagestan sample as major compounds. The results obtained by us, of course, are of scientific interest and practical importance. Thus, the investigated samples of wormwood and their essential oils can be used as sources of such important compounds as lingiverbenone, which has antimicrobial ac-tivity, attractant and repellent activity (A. splendens) and α-bisabolol, which has a great future in combating malignant tumors (A. tschernieviana).

Keywords: 
Artemisia splendens Willd.
Artemisia tschernieviana Bess.
essential oil
longiriverbone
α-bisabolol
artemisia-ketone

It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Berezovskaja T.P., Amel'chenko V.P., Krasnoborov I.M.,
  2. Seryh E.A. Polyni Sibiri. Novosibirsk. Nauka. 1991.
  3. 123 s.
  4. Naqinezhad A., Nabavi S.M., Nabavi S.F., M.A. Ebrahimzadeh M.A. Antioxidant and antihemolytic activities of flavonoid rich fractions of Artemisia tschernieviana Besser // European Review for Medical and Pharmacological Sciences. 2012. V. 16 (Suppl. 3). P. 88−94.
  5. Heshmati A.F., Delazar A., Nazemiyeh H., Esnaashri S., Moghadam S.B. Comparison of the total phenol, flavonoid contents and antioxidant activity of methanolic extracts of Artemisia specigera and A. splendens growing in Iran // Pharmaceutical sciences. 2012. V. 18. №.3. P. 165−170.
  6. Sharma V., Pathania V.L., Singh B., Gupta R.C. GCMS analysis and anti-microbial activity of essential oil of Artemisia minor Jacq. ex Bess. From Lahaul&Spiti (Cold Desert) region of North India // International Journal of Drug Development & Research. 2011. V. 3. № 1. P. 127−139.
  7. Naghavi M.R., Alaeimoghadam F., Ghafoori H. Artemisia species from Iran as valuable resources for medicinal uses // Int. Journal of Biological, Biomolecular, Agricultural, Food and Biotechnological Engineering. 2014. V. 8. № 11. P. 1194−1200.
  8. Abad M.J., Bedoya L.M., Apaza L., Bermejo P. The Artemisia L. Genus: a review of bioactive essential oils // Molecules. 2012. V. 17. P. 2542-2566. doi:10.3390/molecules17032542.
  9. Naemi M., Amjad L., Roozbehani S. A study on the allergenicity of Artemisia deserti flowering taps in Guinea pigs // Int. Journal of Agronomy and Plant Production. 2013. V. 4. № 12. P. 3296−3300.
  10. Juteau F, Masotti V, Bessière J.M, Dherbomez M, Viano J. Antibacterial and antioxidant activities of Artemisia annua essential oil // Fitoterapia. 2002. V. 73. № 6. P. 532−535.
  11. Sayyah M., Nadjafnia L., Kamalinejad M. Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oil // J. Ethnopharmacol. 2004. V. 94. №. 2−3. P. 283−287.
  12. Mohammadi A, Sani T.A., Ameri A.A., Imani M., Golmakani E., Kamali H.H. Seasonal variation in the chemical composition, antioxidant activity, and total phenolic content of Artemisia absinthium essential oils // Pharmacognosy Res. 2015. V. 7. № 4. P. 329–334. doi: 10.4103/0974-8490.158441.
  13. Kordali S., Kotan R., Mavi A., Cakir A., Ala A., Yildirim A. Determination of the chemical composition and antioxidant activity of the essential oil of Artemisia dracunculus and of the antifungal and antibacterial activities of Turkish Artemisia absinthium, A. dracunculus, Artemisia santonicum, and Artemisia spicigera essential oils // J. Agric. Food. Chem. 2005. V. 53. № 24. P. 9452−9458.
  14. Juteau F., Jerkovic I., Masotti V., Milos M., Mastelic J., Bessière J.M., Viano J. Composition and antimicrobial activity of the essential oil of Artemisia absinthium from Croatia and France // Planta Med. 2003. V. 69. № 2. P. 158−161.
  15. Lutgen P. Artemisia ketone, phytosterols and lipid metabolism. 2013. http://www.malariaworld.org/blog/artemisiaketone- phytosterols-and-lipid-metabolism.
  16. Merila J., Hendry A.P. Climate change, adaptation and phenotypic plasticity. The problem and the evidence // Evolutionary Applications. 2014. V. 7. № 1. P. 1−14.
  17. Podlech D., Huber-Morath A., Iranshahr M., Rechinger K.H. Artemisia. In: Flora Iranica: V. 158. Compositae VI − Anthemideae. 1986. 234 r.
  18. Mozaffarian V. Compositae: Anthemideae&Echinopeae,. In: Flora of Iran / Eds. Assadi et al. Research Institute of Forests and Rangelands, Tehran. Iran. 2008. V. 59.
  19. Sisengalieva G.G., Ishmuratova M. Ju., Iskakova Zh.B., Dzhalmahanbetova R.I., Sulejmen E.M. Issledovanie biologicheskoj aktivnosti i anatomicheskogo stroenija Artemisia tschernieviana Besser iz Kazahstana // Estestvennye i matematicheskie nauki v sovremennom mire. 2014. № 17. S. 109−119.
  20. Murtazaliev R.A. Konspekt flory Dagestana / Otv. red. chl.-korr. RANR. V. Kamelin. Mahachkala: «Epoha». 2009. T. III. 304 c.
  21. Kursat M., Civelek S. The investigation of three species belong to Artemisia L. (Asteraceae) grown naturally in Turkey in point of morphological features) // ArtvinCoruh University Faculty of Forestry Journal. 2011. V. 12. № 19. P. 15−25.
  22. Kazemi M., Zand M.R., Roshanaei K., Mehrzad M., Rustaiyan A. Composition of the volatile oils of Artemisia
  23. armenica Lan. And Artemisia splendens Willd. from Iran // J. Essen. Oil Res. 2002. V. 22. № 2. P. 126−128. DOI:10.1080/10412905.2010.9700280.
  24. Afshar F.H., Delazar A., Nazemiyeh H., Esnaashari S. Chemical composition, antioxidant, insecticidal and general toxicity activities of essential oils isolated from the aerial parts of Artemisia spicigera and Artemisia splendens // Res. Pharm. Sci. 2012. V. 7. № 5. P. S786.
  25. Kazemi M., Dakhili M., Rustaiyan A., Larijani K., Ahmadi M.A., Mozaffarian V. Chemical composition antimicrobial activity of Artemisia tschernieviana Besser from Iran // Pharmacognosy Res. 2009. № 1. P. 120–124.
  26. Zanousi M.B.P., Azar P.A., Raeesi M. Chemical composition and antimicrobial activity of essential oils of different organs of three Artemisia species from Iran // Journal of Medicinal Plants Research. 2012. V. 6. № 42. P. 5489−5494. doi: 10.5897/JMPR12.271 .
  27. Shatar S., Nguyen X.D., KarashawaD. Essential oil composition of some Mongolian Artemisia species // Journal of Essential Oil Bearing Plants. 2003. V. 6. № 3. R. 203–206.
  28. Azar P.A., Tehrani M.S., Hosain S.W., Khalilzadeh M.A., Zanousi M.B.P. Solvent-Free microwave extraction of essential oil of Artemisia tschernieviana // Asian Journal of Chemistry. 2012. V. 24. № 11. P. 5388–5390.
  29. Gosudarstvennaja Farmakopeja SSSR. Obschie metody analiza. Lekarstvennoe rastitel'noe syr'e. Izd. 13-e. 2017. http://www.femb.ru/feml.
  30. Abljatsionnye materialy Darzana // Himicheskaja entsiklopedija v 5 tomah. M.: Bol'shaja Rossijskaja Entsiklopedija. 1988. T. 1. 623 s.
  31. Aliev A.M., Radjabov G.K., Musaev A.M. Dynamics of supercriticalextraction of biological active substances from the Juniperus communis var. Saxatillis // The Journal of Supercritical Fluids. 2015. V. 102. P. 66−72.
  32. Aliev A.M., Radjabov G.K., Stepanov G.V. Somposition of Extract of the Juniperus oblonga M. Bieb. Fruits obtained by supercritical CO2 extraction // Russian Journal of Physical Chemistry B. 2013. T. 7. № 7. P. 795−801.