THE SUBSTANTIATION OF ANTIBACTERIAL ACTION OF DENTAL GELS ON THE BASIS OF MONARDA FISTULOSA L. LIQUID EXTRACT

DOI: https://doi.org/10.29296/25877313-2019-01-07
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1
Year: 
2019

I.V. Dukhanina Associate Professor, Yaroslavl State Medical University E-mail: inessaia@rambler.ru А.S. Nikitina Senior Lecturer, Pyatigorsk Medical Pharmaceutical Institute  branch of the FSEI HE «Volgograd State Medical University» E-mail: lina_nikitina@mail.ru N.V. Nikitina Senior Lecturer, Pyatigorsk Medical Pharmaceutical Institute  branch of the FSEI HE «Volgograd State Medical University» E-mail: n_niki7@mail.ru S.А. Feskov Junior Research Scientist, FSGBUN «Order of the Red Banner of Labor Nikitsky Botanical Garden - National Science Center of the Russian Academy of Sciences» (Yalta, Republic of Crimea) E-mail: lina_nikitina@mail.ru V.А. Romanov Dr.Sc. (Med.), Professor, Academician Russian Academy of Natural Sciences, Yaroslavl State Medical University E-mail: microbyama@mail.ru

The study of antibacterial activity of various alcoholic extracts of the herb Monarda fistulosa L. The availability and range of the antimicrobial action was confirmed by the results of studies of extracts by the method of diffusion in agar on the strains of gram-positive and gram-negative microorganisms. A comparative evaluation of antimicrobial activity and a justified selection of the optimal model compositions of dental gels containing the liquid extract of the herb Monarda fistulosa L. It is established that the highest zone of growth inhibition of microorganisms provide gels on the ba-sics of MC and P - CMC. The prospects of the use of phytocomplexes from raw materials Monarda fistulosa L. for the development of medicines with antimicrobial action are shown.

Keywords: 
antimicrobial activity
Monarda fistulosa L. herb
stomatological gel
liquid extract

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