R.M. Radzhabkadiev Junior Resarch Scientist, Federal Research Centre of Nutrition and Biotechnology (Moscow) Е-mail:

Purpose of the study: to evaluate some biochemical blood parameters of athletes, mainly training strength endurance. Materials and methods. We examined 40 elite bobsleigh athletes of both sexes (28 men and 12 women) in the precompetitive period of sports training. The average age of men was 22.1±2.53 years, women  23.7±3.63 years. In the serum studied biochemical parameters activity of alanine amino  (ALT) and aspartate aminotransferase (AST), creatine phosphokinase (CK), creatine phosphokinase MB (CKMB). Results. In both gen-der groups revealed a significant excess of CK activity relative to reference values (on average, 2.9 and 1.9 times, respectively). Creatine kinase activi-ty in men was 44.1% higher than in women (р < 0,05). Also in men, in 47.6% and 23.8% of cases, elevated AST and ALT values were observed, re-spectively, relative to reference intervals. The muscle damage index (CPK/AST) in 95.2% of cases in men and 75% of cases in women was more than 10, which indicates the presence of damage to muscle cells. Conclusions. The data obtained indicate that high values of metabolic biomarkers are characteristic of bobsleighs. This is probably due to mechanical damage to myocytes during intense physical exertion and the development of the cre-atinephosphokinase mechanism of energy supply in athletes of this group.

creatine phosphokinase
alanine aminotransferase
aspartate aminotransferase
muscle damage

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