VERBENA MEDICINAL (VERBENA OFFICINALIS L.): REVIEW OF PHYTOCHEMICAL AND PHARMACOLOGICAL STUDIES

DOI: https://doi.org/10.29296/25877313-2019-11-02
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Issue: 
11
Year: 
2019

O.Yu. Kulyak Ph.D. (Pharm.), Research Scientist, Laboratory of Atomic Molecular Bioregulation and Selection, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow); Lomonosov Moscow State University, Faculty of Fundamental Medicine E-mail: Kulyak-Olesya@mail.ru G.V. Adamov Post-graduate Student, Research Scientist, Laboratory of Atomic Molecular Bioregulation and Selection, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow) A.I. Radimich Senior Research Scientist, Department of Phytochemistry and Standardization, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow) O.L. Saibel Ph.D. (Pharm.), Head of the Center for Chemistry and Pharmaceutical Technology, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow)

As part of the implementation of the government strategy for development of the pharmaceutical industry of Russian Federation for the period until 2030, creation of drugs, including herbal origin has priority. Interest in herbal remedies remains relevant today due to its mild effect, low toxicity and the possibility of long-term use to prevent and treat various diseases. In this regard, the goal of our work is to generalize the available literature da-ta on the phytochemical composition, toxicity, and pharmacological activity of the Verbena officinalis L., the Verbenaceae. In traditional medicine of dif-ferent countries, various pharmacological effects of the herb Verbena officinalis are indicated. Numerous preclinical and clinical studies confirm its an-tibacterial, anti-inflammatory, anthelmintic, anticonvulsant, gastroprotective, neuro- and cardioprotective and antitumor activities. Herb Verbena offici-nalis, along with lemon verbena leaves, is represented in the European, British Herbal, American Herbal and Chinese Pharmacopoeias, but in the Rus-sian Federation there are no data on registered single-component preparations, however, two biologically active additives containing Verbena officinalis are registered. Thus, we consider it necessary to study promising raw materials growing in the Russian Federation with the possibility of developing drugs based on it.

Keywords: 
verbena officinalis
biologically active substances
pharmacological activity
rutin
tinctura Eucalypti
Chlorophyllipt

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