ANALYSIS OF LEVEL OF LEPTIN CIRCULATING IN BLOOD IN THE YAKUT POPULATION

DOI: https://doi.org/10.29296/25877313-2020-05-02
Issue: 
5
Year: 
2020

A.A. Nikanorova Post-graduate Student, Institute of Natural Science, North-Eastern Federal University named M.K. Ammosov; Junior Research Scientist, Yakut Scientific Center of Complex Medical Problems (Yakutsk) E-mail: nikanorova.alena@mail.ru N.A. Barashkov Ph.D. (Biol.), Head of Laboratory, Yakut Scientific Center of Complex Medical Problemsc S.S. Nakhodkin Engineer-researcher, Laboratory of Molecular Biology, Institute of Natural Sciences, North-Eastern Federal University named M.K. Ammosov (Yakutsk) V.G. Pshennikova Ph.D. (Biol.), Head of Laboratory, Yakut Scientific Center of Complex Medical Problems (Yakutsk) A.V. Solovyev Ph.D. (Biol.), Junior Research Scientist, Laboratory of Molecular Biology, Institute of Natural Sciences, North-Eastern Federal University named M.K. Ammosov (Yakutsk) G.P. Romanov Engineer, Laboratory of Molecular Biology, Institute of Natural Sciences, North-Eastern Federal University named M.K. Ammosov (Yakutsk) S.S. Kuzmina Ph.D. (Biol.), Associate Professor, Department of Biology, Institute of Natural Sciences, North-Eastern Federal University named M.K. Ammosov (Yakutsk) N.N. Sazonov Dr.Sc. (Biol.), Professor, Department of Biology, Institute of Natural Sciences, North-Eastern Federal University named M.K. Ammosov (Yakutsk) S.A. Fedorova Dr.Sc. (Biol.), Head of the Laboratory of Molecular Biology, Institute of Natural Sciences, North-Eastern Federal University named M.K. Ammosov (Yakutsk)

Relevance. Adipose tissue is considered an endocrine organ that produces several hormonally active substances, including the hormone leptin. This hormone plays a key role in regulating energy homeostasis and thermoregulation and may be involved in microevolutionary mechanisms of human adaptation to cold climates. The purpose of this work is to analyze the levels of leptin in the blood of young Yakut people living in the Republic of Sakha (Yakutia). Material and methods. The sample included Yakuts 18–30 years old with a total population of 281 people (186 women and 95 men). For each par-ticipant, the body mass index (BMI) was calculated, and the level of leptin in the blood serum was determined. Results. The average leptin level in women was 18.95±0.9 ng/ml, in men 6.57±0.88 ng/ml. In the Yakut population, previously known leptin sexual dimorphism (p

Keywords: 
leptin
thermoregulation
meta-analysis
Eastern Siberia
Yakut people

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