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CRITERIA FOR EVALUATING THE QUALITATIVE AND QUANTITATIVE CHARACTERISTICS OF MICROCAPSULES

DOI: https://doi.org/10.29296/25877313-2021-12-02
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Issue: 
12
Year: 
2021

O.A. Semkina Ph.D. (Pharm.), All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow, Russia) E-mail: semkinaolga@gmail.com O.M. Beloshapkina Post-graduate Student, Lomonosov Moscow State University; All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow, Russia) M.A. Dzhavakhyan Dr.Sc. (Pharm.), All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow, Russia)

The review presents material on the peculiarities of methods for assessing the quality of microcapsules of drug substances and the potential applica-tion of formal techniques and additional tests proposed for active pharmaceutical substances enclosed in microcapsules. We analyzed domestic and foreign sources of open access literature; the following digital databases were used: PubMed, Elibrary, CyberLenincka and the Google Scholar search engine. The effective tests proposed for microencapsulated substances and the need for additional tests for microcapsules depending on their compo-sition and purpose were identified. Opportunities of microcapsules standardization as a dosage form for effective evaluation and understanding of quali-tative and quantitative characteristics while considering microparticles as a pharmaceutical substance and a dosage form intended for use were de-scribed.
Keywords: 
microcapsules
encapsulation
standardization
quality assessment
microencapsulation
trials

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References: 
  1. Garg A., Chhipa K., Kumar L. Microencapsulation Techniques in Pharmaceutical Formulation. European Journal of Pharmaceutical and Medical Research. 2018; 5(3): 199–206.
  2. Chueshov V.I., Gladuh E.V., Sajko I.V. Tehnologija lekarstv promyshlennogo proizvodstva. V 2-h chastjah. Vinnica: Novaja kniga. 2014. 696 s.
  3. Carvalho I.T., Estevinho B.N., Santos L. Application of microencapsulated essential oils in cosmetic and personal healthcare products – a review. International Jour-nal of Cosmetic Science. 2016; 38(2): 109–119.
  4. Farheen T., Shaikh A., Shahi S. A Review on a Process: Microencapsulation. Int. J. Pharma Res. Health Sci. 2017; 5(5): 1823–1830.
  5. Surini S., Nursatyani K., Ramadon D. Gel formulation containing microcapsules of grape seed oil (Vitis vinifera L.) for skin moisturizer. Journal of Young Pharmacists. 2018; 10(1): 41–47.
  6. Neubauer M.P., Poehlmann M., Fery A. Microcapsule mechanics: From stability to function. Advances in Colloid and Interface Science. 2014; 207: 65–80.
  7. Lengyel M., Kállai-Szabó N., Antal V. et al. Microparticles, microspheres, and microcapsules for advanced drug delivery. Scientia Pharmaceutica. 2019; 87(20): 1–31.
  8. Prakash K., Raju P.N., Shanta K.K. et al. Preparation and characterization of lamivudine microcapsules using various cellulose polymers. Tropical Journal of Pharma-ceutical Research. 2007; 6(4): 841–847.
  9. Antonio-Gomez M.V., Salinas-Moreno Y., Hernandez-Rosas F. et al. Optimised extraction, microencapsulation, and stability of anthocyanins from Ardisia compressa K. fruit. Pol. J Food Nutr Sci. 2021; 71(3): 299–310.
  10. Stepanova E.F., Kim M.E., Murzagulova K.B., Evseeva S.B. Mikrokapsuly: perspektivy ispol'zovaniya v sovremennoj farmacevticheskoj praktike. Sovrem. probl. nauki i obraz. 2014; 5: 1–8.
  11. Pudziuvelyte L., Marksa M., Jakstas V., et al. Microencapsulation of Elsholtzia ciliata herb ethanolic extract by spray-drying: impact of resistant-maltodextrin com-plemented with sodium caseinate, skim milk, and beta-cyclodextrin on the quality of spray-dried powders. Molecules. 2019; 24(1461): 1–22.
  12. Yan X., Zhao W., Qian X. Effect of water-based emulsion core microcapsules on aging resistance and self-repairing properties of water-based coatings on linden. Applied Sciences. 2021; 11(10): 1–15.
  13. Polkovnikova Ju.A., Slivkin A.I. Sposob kolichestvennogo opredelenija fenibuta v mikrokaspulah metodom kapilljarnogo jelektroforeza. Patent Rossii № 2642275.2006. Bjul. № 3.
  14. Manjanna K.M., Shivakumar B., Pramod Kumar T.M. Microencapsulation: An acclaimed Novel Drug-Delivery System for NSAIDs in arthritis. Critical Reviews in Thera-peutic Drug Carrier Systems. 2010; 27(6): 501–532.
  15. Musabaeva B.H., Murzagulova K.B., Kim M.E. i dr. Poluchenie mikrokapsul protivotuberkuleznyh preparatov na osnove biopolimerov i polijelektrolitov. Farmacija i farmakologija. 2017; 5(2): 164–176.
  16. Devi M., Dutta S., Hinai A.H., Feroz S. Studies on encapsulation of Rifampicin and its release from chitosan-dextran sulfate capsules. Korean Journal of Chemical En-gineering. 2015; 32(1): 118–124.
  17. Grehnjova E.V., Vlasova V.V. Osobennosti mikrokapsulirovanija oksitetraciklina i ceftriaksona v dvojnye obolochki. Auditorium. 2017; 2: 1–5.