PEPTIDE THERAPY IN CLINICAL PHARMACOLOGY: CURRENT STATE AND PROMISING DIRECTIONS OF DEVELOPMENT

DOI: https://doi.org/10.29296/25877313-2022-02-01
Issue: 
2
Year: 
2022

N.T. Arkhincheeva Post-graduate Student, Department of Pharmacology and Traditional Medicine, Medical Institute, Buryat State University (Ulan-Ude, Russia) Е-mail: norjima01@mail.ru I.M. Balkhaev Dr.Sc. (Med.), Associate Professor, Medical Institute, Buryat State University (Ulan-Ude, Russia) E-mail: ill.balkhaev@mail.ru

Abstract: Insulin therapy initiated the use of peptides in incurable diseases at the beginning of the 20th century. Over time, peptide science has evolved in sync with other scientific discoveries and has finally expanded its view beyond the traditional focus on human endogenous peptides to re-veal a broader range of peptide agents identified from other resources or through medicinal chemistry. The article is a literary review of publications in the Russian scientific electronic library eLIBRARY and in the PubMed library of the USA National Center for Biotechnology Information (NCBI). As a result of the analysis, the formulation of peptide therapy, the current state of the development of peptide therapy, the strengths and weaknesses of peptides as drugs, and emerging new opportunities in the design and development of peptide drugs are outlined.

Keywords: 
peptide therapy
peptides
peptides penetrating into the cell
epigenetic regulation

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