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EVALUATION OF THE EFFICIENCY OF USE OF A BIOLOGICALLY ACTIVE SUPPLEMENT BASED ON THE EXTRACT OF GALEGA OFFICINALIS IN THE COMPLEX THERAPY OF TYPE 2 DIABETES MELLITUS

DOI: https://doi.org/10.29296/25877313-2022-09-06
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Issue: 
9
Year: 
2022

V.N. Burkova
Dr.Sc. (Chem.), Director of Science and Innovation, "Biolit" LLC (Tomsk, Russia)
V.P. Sergun
Ph.D. (Chem.), Director, "Biolit" LLC (Tomsk, Russia)
A.A. Ivanov
Ph.D. (Chem.), Head of Research Department, "Biolit" LLC (Tomsk, Russia)
E-mail: infobiolit@yandex.ru
Yu.G. Samoylova
Dr.Sc. (Med.), Professor, Department of Endocrinology and Diabetology, Siberian State Medical University (Tomsk, Russia)
O.A. Oleinik
Ph.D. (Med.), Associate Professor, Department of Faculty Therapy with a Course of Clinical Pharmacology,
Siberian State Medical University (Tomsk, Russia)

Relevance. Diabetes mellitus is one of the most common chronic diseases in the world. The vast majority of patients suffering from this pathology have type 2 diabetes mellitus, for the treatment of which drugs with various effects on metabolic processes are used. In recent years, the interest in a study of medicinal plants with antidiabetic activity has grown in the scientific and medical community. The purpose of this work was to study the efficiency and safety of the complex application of a biologically active supplement (dietary supplement) to food based on the extract of the herb Galega officinalis L. in disorders of carbohydrate metabolism in patients with type 2 diabetes mellitus. Results. When using dietary supplements in combination with basic therapy in patients with type 2 diabetes mellitus, there was a significant im-provement in glycemic variability indices by the end of the study. Intraday fluctuations in glucose levels significantly decreased, the frequency of hy-perglycemic phenomena decreased, glycemic indices were within the target range. The main indicator of diabetes mellitus compensation is the de-termination of the level of glycated hemoglobin HbA1c. In the group of patients with dietary supplements compared with basic therapy, there was a significant decrease in the level of glycated hemoglobin: HbA1c in the group of patients with dietary supplements decreased by 0.8%, and in the group of standard therapy increased by 0.05%. This indicates a positive dynamics of the glycemic profile and a decrease in the rate of development of late complications of diabetes mellitus. Conclusion. Thus, the continuous monitoring of glycemia testified to the efficiency and safety of the use of dietary supplements based on the extract of the herb Galega officinalis in the complex therapy of type 2 diabetes mellitus.
Keywords: 
type 2 diabetes mellitus
complex therapy
Galega officinalis
glycemia

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