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STUDYING THE FEATURES OF ACCUMULATION OF FLAVONOIDS IN WORMWOOD HERB OF BITTER SYNANTROPIC FLORA OF THE ROSTOV REGION

DOI: https://doi.org/10.29296/25877313-2023-01-02
Issue: 
1
Year: 
2023

Y.A. Selivanova
Assistant, Department of Pharmaceutical Chemistry and Pharmaceuticals Technology,
Voronezh State University (Voronezh, Russia)
E-mail: u.a.selivanova@yandex.ru
N.A. Dyakova
Ph.D. (Biol), Associate Professor, Department of Pharmaceutical Chemistry and Pharmaceutical Technology,
Voronezh State University (Voronezh, Russia)
E-mail: Ninochka_V89@mail.ru
A.I. Slivkin
Dr.Sc. (Pharm.), Professor, Head of Department of Pharmaceutical Chemistry and Pharmaceutical Technology,
Voronezh State University (Voronezh, Russia)
E-mail: slivkin@pharm.vsu.ru
A.A. Vervikina
Student, Faculty of Pharmacy,
Voronezh State University (Voronezh, Russia)
E-mail: alisa.vervikina@yandex.ru

Anthropogenic impact on medicinal plants is an important factor that affects the synthesis of secondary metabolites. With an increase in anthropogen-ic load, additional synthesis of secondary metabolites increases, primarily flavonoids, which play an important and obvious role in protecting plants from stress. The aim of the study was to study the features of the accumulation of flavonoids in the herb wormwood synanthropic flora of the Rostov region. Material and methods. Samples of medicinal plant material of wormwood herb collected in Morozovsky district of Rostov region were studied. Wormwood herb was collected and dried during the beginning of flowering (end of June - beginning of July 2021). The content of the sum of flavonoids in terms of rutin in selected samples of wormwood herb was determined three times by the standard pharmacopoeial method on a spectrophotometer SF-2000. Results. The study of vegetable raw materials harvested in the roadside zone of a slow road (IV category) with slow traffic and a railway showed a di-rect dependence on a decrease in the content of flavonoids with an increase in the distance from highways. Conclusion. According to the studies, it can be concluded that moderate anthropogenic impact, which is characterized by the release of various eco-toxicants into the environment, can induce the biosynthesis of flavonol compounds. However, under conditions of complex toxic stress (near the cate-gory IA highway with high transport traffic), the plant antioxidant system may be inhibited, which is expressed by the suppression of the production of polyphenols.

Keywords: 
Rostov region
wormwood bitter
flavonoids
rutin.

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