Download full text PDF

F.M. Khazieva Ph.D (Biol.), Head. Department of Agrobiology and Selection, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow). E-mail: I.N. Korotkikh Ph.D. (Agric.), Leading Research Scientist, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow). E-mail: V.I. Ossipov Dr.Sc. (Biol.), Chief Research Scientist, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow); Natural Compounds Research Group, Department of Chemistry, University of Turku (Finland) E-mail:

Origanum vulgare L. varietal plants belong to certain morphotypes, characterized by a genetically fixed complex of constant features (height, color of organs, type of growth, biometric indicators). Determined the structure and content of individual compounds of essential oil of three varieties of O. vulgare (‘Raduga’, ‘Slavnitca’, ‘Zima’) the biological collection of VILAR. T. EO analysis was performed by gas chromatography and mass spectrometry (GC-MS). As a result, 120 individual compounds were found in the composition of O. vulgare EO and 62 compounds were identified. The main compounds of EO are the 11 compounds: terpinene-4-ol (16.4%), β-caryophyllene (12.4%), germacrene D (9.7%), caryophyllene oxide (8.2%), spathulenol (7.7%) and α-cadinol (6.0 %), γ-terpinene (2.9%) and δ-cadinol (2.8%) and α-humulen (2.2%), δ-cadinene (1.9%) and α-terpineol (1.7%). They account for 71.9% of the total content of EO compounds. Compounds from the group of sesquiterpenes predominate in all varieties, but their maximum content was found in the variety ‘Zima’ (51%). The variety ‘Slavnitca’ the content of compounds monoterpenes 6 times more than the variety ‘Raduga’ and 14 times more than the variety ‘Zima’. The highest content of phenolic compounds was found in the ‘Raduga’ variety. The results suggest the presence of O. vulgare varietal chemotypes not only in connection with the content of phenolic components (thymol and carvacrol), but also in connection with the total content of compounds of other groups (monoterpenes and sesquiterpenes), characterized by specific pharmacological activity. All varieties of O. vulgare are related to low-phenol chemotypes (thymol and carvacrol content was less than 1%).

Origanum vulgare L.
essential oil
gas-liquid chromatography

It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

  1. Manohar V., Ingram C., Gray J., Talpur N.A., Echard B.W., Bagchi D., Preuss H.G. Antifungal activities of origanum oil against Candida albicans // Molecular and Cellular Biochemistry. 2001; 228; 12: 111–117.
  2. Özkan A., Erdoğan A. A comparative evaluation of antioxidant and anticancer activity of essential oil from Origanum onites (Lamiaceae) and its two major phenolic components // Turk. J. Biol. 2011; 35; 6: 735–742.
  3. Dosta N.I., Nitkin D.M., Voshchula V.I., Lelyuk V.YU., Gaponenko A.D. Sovremennye vozmozhnosti ispol'zovaniya «Urolesana» v lechenii urologicheskoj patologii // Recept. 2011. T. 80. № 6. S. 151–158.
  4. Korotkih I.N., Hazieva F.M., Tockaya S.A. Cennye morfotipy dushicy // Kartofel' i ovoshchi. 2015. № 4. S. 24–25.
  5. Schauer N., Steinhauser D., Strelkov S. et al. GC-MS libraries for the rapid identification of metabolites in complex biological samples // FEBS Letters. 2005; 579; 6: 1332–1337.
  6. Falco E., Mancini E., Roscigno G., Mignola E., Taglialatela-Scafati O., Senatore F. Chemical composition and biological activity of essential oils of Origanum vulgare L. subsp. vulgare L. under different growth conditions // Molecules. 2013; 18; 12: 14948–1460.
  7. Tkachev A.V. Issledovanie letuchih veshchestv rastenij / Novosibirsk: Izdatel'sko-poligraficheskoe predpriyatie «Ofset». 2008. 969 s.
  8. Aligiannis N., Kalpoutzakis E., Mitaku S.,Chinou I. Composition and antimicrobial activity of the essential oils of two Origanum species // J. Agric. Food Chem. 2001; 49; 9: 4168–4170.
  9. Shelepova O.V., Voronkova T.V., Kondrat'eva V.V., Olekhnovich L.S. Izmenenie sostava efirnogo masla rastenij dushicy obyknovennoj (Origanum vulgare L.) pri abioticheskom stresse (zagryaznenii okruzhayushchej sredy) / Materialy I Mezhd. nauchn. konf.: Netradicionnye, novye i zabytye vidy rastenij: nauchnye i prakticheskie aspekty kul'tivirovaniya. Kiev. 2013: 353–356