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COMPONENT COMPOSITION OF ESSENTIAL OILS AND ANTIOXIDANT ACTIVITY OF HYSSOPUS OFFICINALIS L. CULTIVARS INTRODUCED IN THE MOUNTAINOUS CONDITIONS OF DAGESTAN

DOI: https://doi.org/10.29296/25877313-2020-12-04
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Issue: 
12
Year: 
2020

M.K. Kuramagomedov Ph.D. (Biol.), Senior Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of the Russian Academy of Sciences (Makhachkala) A.M. Aliev Senior Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of the Russian Academy of Sciences (Makhachkala); Institute of Physics, Dagestan Federal Research Center of the Russian Academy of Sciences (Makhachkala) E-mail: aslan4848@yahoo.com F.I. Islamova Ph.D. (Biol.), Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of the Russian Academy of Sciences (Makhachkala) E-mail: fatimaisl@mail.ru M.M. Mamalieva Junior Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of the Russian Academy of Sciences (Makhachkala) E-mail: mamalieva19@mail.ru G.K. Radjabov Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of the Russian Academy of Sciences (Makhachkala) Е-mail: chemfarm@mail.ru A.M. Musaev Senior Research Scientist, Head of Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of the Russian Academy of Sciences (Makhachkala) E-mail: musaev-58@list.ru

Relevance. Currently, there is an acute problem of strengthening the raw material base of essential oil and spicy-aromatic plants. For the Republic of Dagestan, the culture of Hyssopus officinalis L. is new and unexplored in mountain conditions. We are screening crops that can be used to restore ter-raced farming, a traditional mountainous industry that is now in deep decline and can be used in the pharmaceutical and food industries. Purpose of the research. Comparative study of the component composition and antioxidant activity in varieties Hyssopus officinalis L. introduced in the mountainous conditions of Dagestan and their comprehensive assessment as possible crops for terraced farming. Material and methods. The objects of study are four varieties: «Accord», «Goluboy», «Dachny lekar», «Otradny». Essential oils were obtained by steam distillation. The composition of essential oils was determined by gas chromatography with a mass spectrometric detector. To determine antiox-idants, the amperometric method was used on a «Tsvet Yauza 01-AA». Results. It has been established that the content of essential oil of the studied varieties ranges from 0,4 to 0,6 %. A high content in all varieties of pi-nocampheon was noted, as well as a relatively high content of pinocarvon in the essential oil of the «Otradnaya» variety. The major components beta-trans-ocimene and alpha-elemol are present only in the «Dachny lekar» essential oil. Components such as myrtenol and pinocarvone are present in the two varieties of essential oils «Accord» and «Otradnaya». Antioxidant activity in varieties varies within 31,7–49,5 mg/g. Conclusions. All varieties belong to the pinocampheon chemotype. The significant content of major components in the four types of essential oils can be considered as their potential resource for the production of essential oils of various uses. The obtained data on antioxidants should be taken into account when evaluating varieties as a source of antioxidants. Plants are resistant to return frosts and tolerate drought well in mountain-valley and mid-mountainous Dagestan.
Keywords: 
medicinal hyssop
essential oil
antioxidants
pinocamphene
beta-pinene
amperometric method
gas chromatography-mass spectrometry

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References: 
  1. Kalinchenko L.V., Malankina E.L., Kozlovskaja L.N. Sravnitel'naja ocenka produktivnosti issopa lekarstvennogo (Hyssopus officinalis L.) v zavisimosti ot sorta i proishozhdenija obrazca. Izvestija TSHA. 2013. V.5.: 171–176.
  2. Malankina E.L. Agrobiologicheskoe obosnovanie povyshenija produktivnosti jefironosov iz semejstva Jasnotkovye v uslovijah Nechernozem'ja Rossijskoj Federacii. Diss. dokt. s-h nauk. 2007. 345 s.
  3. Kalinchenko L.V. Agrobiologicheskie osobennosti issopa lekarstvennogo (Hyssopus officinalis L.) i puti povyshenija produktivnosti kul'tury v uslovijah Nechernozemnoj zony. Diss. kand. s-h nauk. M. 2013. 27 s.
  4. Svoboda K.P., Salambosi B., Deans S.G., Hethelyi E. Agronomichal and photochemical investigation of Hyssopus officinalis L. Agric sci Finl. 1993: 29–33.
  5. Lubansandorzhieva P.B., Atunova T.A. Antioksidantnaja aktivnost' rastitel'nyh srezov. Farmacija. 2015; (6): 43–45.
  6. Kalinichenko L.V., Malankina E.L., Kozlovskaja L.N. Sravnitel'naja ocenka produktivnosti issopa lekarstvennogo (Hyssopus officinalis L.) v zavisimosti ot sorta i proishozhdenija obrazca. Izvestija Timirjazevskoj sel'skohozjajstvennoj akademii. 2013; 5: 171–176.
  7. Nikitina A.S., Popova O.I., Popov I.V., Nikitina N.V. Razrabotka i nauchnoe obosnovanie kompleksnogo ispol'zovanija rastitel'nogo syr'ja issopa lekarstvennogo i zmeegolovnika moldavskogo. Sovremennye problemy nauki i obrazovanija. 2011; 2: 25–29.
  8. Bespal'ko L.V., Harchenko V.A., Shevchenko Ju.P., Ushakova I.T. Issop lekarstvennyj (Hyssopus officinalis L.). Ovoshhi Rossii. 2016; 2: 60–63.
  9. Kovalenko N.A., Ahramovich T.I., Supichenko G.N., Sachivko T.V., Bosak V.N. Antibakterial'naja aktivnost' jefirnyh masel issopa lekarstvennogo. Himija rastitel'nogo syr'ja. 2019; 1: 191–199.
  10. Velikorodov A.V., Kovalev V.B., Kurbanova F.H., Shhepetova E.V. Himicheskij sostav jefirnogo masla Hyssopus officinalis L., kul'tiviruemogo v Astrahanskoj oblasti. Himija rastitel'nogo syr'ja. 2015; 3: 71–76.
  11. Sen' T.V. Farmakognosticheskoe izuchenie issopa lekarstvennogo: Dis. avtoref. …. kand. farm. nauk. Kursk: gos. med. unt, 2007.25 s.
  12. Yildirim A., Oktay M., Bifalog Lu Y. (GuLiyev) The antioxidant activities of the Leaves of Cydonia vulgaris. Turkish J. Med. Sci. 2001; 31: 23–27.
  13. Amarowicz R., Pegg R.B., Moghadam P.R., Barl B. Weil J.A. Free radical scavenging capacity and antioxidant activity of selected Plant Species from the Canadian prairies. Food Chem. 2004; 84(4): 551–562.
  14. Alinezhad H., Azimi R., Zare M. et al. Antioxidant and antihemolytic activities of ethanolic extract of flowers, leaves, and stems of Hyssopus officinalis L. Var. angustifolius. International journal of food properties. 2013; 16(5): 1169–1178.
  15. Fathiazad F., Mazandarani M., Hamedeyazdan S. Phytochemical analysis and antioxidant activity of Hyssopus officinalis L. from Iran. Advanced Pharmaceutical Bulletin. 2011; 1(2): 63.
  16. Džamić A.M., Soković M., Novaković M.M. et al. Composition, antifungal and antioxidant properties of Hyssopus of-ficinalis L. subsp. pilifer (Pant.) Murb. essential oil and deodorized extracts. Industrial Crops and Products. 2013; 51: 401–407.
  17. Hristova Y., Wanner J., Jirovetz L., Stappen I., Iliev I., Gochev V. Chemical composition and antifungal activity of essential oil of Hyssopus officinalis L. from Bulgaria against clinical isolates of Candida species. Biotechnology & Biotechnological Equipment. 2015; 29(3): 592–601.
  18. Jashin A.Ja. Inzhekcionno-protochnaja sistema s amperometricheskim detektorom dlja selektivnogo opredelenija antioksidantov v pishhevyh produktah i napitkah. Rossijskij himicheskij zhurnal. 2008; 1(2): 130–135.
  19. Zykova I.D., Efremov A.A. Sostav jefirnogo masla nadzemnoj chasti v raznyh fazah razvitija rastenij. Rastitel'nye resursy. 2012; 48(V3): 370–375.
  20. Gorjunova Ju.D. Vlijanie jekologicheskih faktorov na soderzhanie v rastenijah nekotoryh antioksidantov. Avtoref. diss. … kand. biol. nauk. Kaliningrad. 2009.