THE RELATIONSHIP OF PHYSICAL ACTIVITY WITH THE INDICATORS OF ZINC AND SELENIUM METABOLISM IN EXPERIMENTAL ANIMALS

DOI: https://doi.org/10.29296/25877313-2021-04-07
Issue: 
4
Year: 
2021

A.A. Skalny Assistant, Department of Medical Elementology, Medical Institute, Peoples' Friendship University of Russia (Moscow, Russia)

The aim of the study. To study the effect of physical activity and additional administration of zinc on the level of zinc and selenium in rats. Material and Methods. The study was performed on 32 males of the Wistar line were divided into four groups: a control group, exposed to physical activity, receiving zinc (15 mg/kg of weight in the form of zinc asparaginate), exposed to physical activity and receiving zinc. The content of zinc and selenium in organs and tissues was evaluated by inductively coupled plasma mass spectrometry (ICPMS). Results. Physical activity significantly reduced the concentration of zinc in skeletal muscle, kidneys, and wool, and selenium in the liver, heart mus-cle, skeletal muscle, and kidneys of rats. At the same time, physical activity led to an increase in the content of zinc in the liver, and selenium - in the blood serum and hair of rats. The additional administration of zinc reduced the increased zinc content in the liver, kidneys, heart muscle, and fur in the rats exposed to physical ex-ertion. With the additional introduction of zinc, selenium reserves began to increase in the group of animals with physical activity. Conclusions. The additional administration of zinc had a positive effect on the body of rats during physical exertion. This may be due not only to changes in zinc metabolism, but also to the regulation of selenium metabolism, as well as their biological effects.

Keywords: 
zinc
selenium
physical activity
asparaginate
ICP MS

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