Нажмите на эту строку чтобы перейти к Новостям сайта "Русский врач"

Перейти
на сайт
журнала
"Врач"
Перейти на сайт журнала "Медицинская сестра"
Перейти на сайт журнала "Фармация"
Перейти на сайт журнала "Молекулярная медицина"
Перейти на сайт журнала "Вопросы биологической, медицинской и фармацевтической химии"
Журнал включен в российские и международные библиотечные и реферативные базы данных

ВАК (Россия)
РИНЦ (Россия)
Эко-Вектор (Россия)

EVALUATION OF THE VARIABILITY OF SOME PHENOLIC COMPOUNDS IN THE DAGESTAN SAMPLES OF TEUCRIUM CHAMAEDRYS L

DOI: https://doi.org/10.29296/25877313-2021-08-06
Download full text PDF
Issue: 
8
Year: 
2021

F.A. Vagabova Ph.D. (Eng.), Senior Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of RAS (Makhachkala, Russia) Е-mail: fazina@mail.ru G.K. Radjabov Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of RAS (Makhachkala, Russia) Е-mail: chemfarm@mail.ru A.M. Musaev Head of Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of RAS (Makhachkala, Russia) Е-mail: musaev-58@lust.ru F.I. Islamova Ph.D. (Biol.), Senior Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical garden, Dagestan Scientific Center of RAS (Makhachkala, Russia) Е-mail: fatimaisl@mail.ru

For the first time, the results of the total content of some phenolic compounds of 70% water-ethanol extracts of the aboveground part of the Teucrium chamaedrys L. and the assessment of their variability depending on the altitude factor in the natural conditions of Dagestan are presented. The material for the study was collected during the flowering phase in 2013. The content of flavonoids and anthocyanins was determined by spectrophotometric method on SF-56. Total antioxidants – amperometric method. The content of accumulation of phenolic compounds in the aboveground part of T. chamaedrys varies in the range of 2.023.06% (the sum of flavonoids); 0.310.43 % (the sum of anthocyanins); 4.359.64 mg/g (the sum of antioxi-dants), depending on the population. The influence of the altitude factor on the accumulation of phenolic compounds showed a multi-vector direction, with a significant positive relationship between the altitude above sea level and the content of total antioxidants. In addition, a direct correlation was found between the content of flavonoids and antioxidants, which indicates the key role of flavonoids in the antioxidant status of T. chamaedrys. Statis-tical methods of analysis made it possible to reveal a greater difference in the variability of the content of phenolic compounds by populations than within populations. Based on the classification matrix, it was possible to divide all samples into separate isolated populations. The results obtained can be used both in the theoretical aspect (revealing the mechanisms of variability of biochemical parameters from abiotic factors), and in the applied meaning
Keywords: 
Teucrium chamaedrys L.
phenolic compounds
flavonoids
anthocyanins
antioxidants
population
altitude gradient

It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Litvinskaja S.A., Murtazaliev R.A. Flora Severnogo Kavkaza. M.: Fiton XXI. 2013; 688.
  2. Murtazaliev R.A. Konspekt flory Dagestana. Otv. red. chl.-korr. RANR.V. Kamelin. Mahachkala: «Jepoha». 2009; 3: 304.
  3. Pavlova D., Karadjova I. Chemical analysis of Teucrium species (Lamiaceae) growing on serpentine soils in Bulgaria. Journal of Plant Nutrition and Soil Science. 2012; 175(6): 891–899.
  4. Bedir E., Manyam R., Khan I.A. Neo-clerodanediterpenoids and phenylethanoid glycosides from Teucriumchamaedrys L. Phytochemistry. 2003; 63(8): 977–983.
  5. Juan R., Pastor J., Millán F., Alaiz M., Vioque J. Amino acids composition of Teucriumnutlet proteins and their sys¬tematic significance. Ann. bot. 2000; 94(4): 615–621. DOI: 10.1093/aob/mch181.
  6. Morteza-Semnani K., Akbarzadeh M., Rostami B. The essen¬tial oil composition of Teucrium chamaedrys L. from Iran. Flavour and Fragrance J. 2005; 20(5): 544–546.
  7. Muselli A., Desjobert J.M., Paolini J., Dessi M.A., Bernardini A.F., Costa J. Chemical composition of the essential oils of Teucrium chamaedrys L. from Corsica and Sardinia. J. of Essential Oil Research. 2009; 21: 138–143.
  8. Ozel M.Zl., Gogus F., Lewis A.C. Determination of Teucrium chamaedrys volatiles by using direct thermal desorption-com¬prehensive two-dimensional gas chromatography-time-offlight mass spectrometry. J. Chromatogr A. 2006; 1114(1): 164–169.
  9. Krishna Kumari G.N., Aravind S., Balachandran J., Ganesh M.R., Soundarya D.S., Rajan S.S., Malathi R., Ravikumar K. Antifeedant neo-clerodanes from Teucrium tomentosum Heyne. (Labiatae). Phytochemistry. 2003; 64(6): 1119–1123.
  10. Rudakova Ju.G. Izuchenie antimikrobnogo dejstvija izvlechenij iz travy Teucrium polium L. (Lamiaceae). Farmacija i farmakologija. 2014; 3(4): 41–43.
  11. Asna M.C., Anadanovic-Brunet, Djilas S.M., Gordana S., Etkovic C., Tumbas V.T., Mandic A.I., Anadanovic V.M.C. Antioxidant activities of different Teucrium monta-num L. ext¬racts. International Journal of Food Science and Technology. 2006; 41: 667–673. DOI:10.1111/j.1365-2621.2006.01133.x.
  12. Martino L., Formisano C., Mancini E., Feo V., Piozzi F., Rigano D., Senatore F. Chemical composition and phytotoxic effects of essential oils from four Teucrium species. Natural product communications. 2010; 5(12): 1969–1976.
  13. Makarevich A.M., Shutova A.G., Spiridovich E.V., Reshetnikov V.N. Funkcii i svojstva antocianov rastitel'nogo syr'ja. Trudy BGU. 2010; 4(2): 1–11.
  14. Hammerstone J.F., Lazarus S.A., Schmitz H.H. Procyanidin content and variation in some commonly consumed foods. J. Nutr. 2000; 130: 20864–20924.
  15. Pier-Giorgio Pietta. Flavonoids as antioxidants. J. Nat. Prod. 2000; 63: 1035–1042.
  16. Gangwal A. Extraction, estimation fad thin layer chromato¬graphy of flavonoids: A review. World Journal of Pharmacy and Pharmaceutical Sciences. 2013; 2(3): 1099–1106.
  17. Khan T.A., Mazid M., Mohammad F. Status of secondary plant products under abiotic stress: an overview. Journal of Stress Physiology & Biochemistry. 2011; 7(2): 75–98.
  18. Poljakova L.V, Ershova Je.A. Izmenchivost' fenol'nyh soedinenij u nekotoryh travjanistyh i drevesnyh rastenij ot mezhpopuljacionnogo do vnutriindividual'nogo (jendogennogo) urovnja. Himija rastitel'nogo syr'ja. 2000; 1: 121–129.
  19. Gosudarstvennaja farmakopeja, XI. M. 1998; 1, 2; 336.
  20. Jashin A.Ja. Inzhekcionno-protochnaja sistema s amperometricheskim detektorom dlja selektivnogo opredelenija antioksidantov v pishhevyh produktah i napitkah. Rossijskij himicheskij zhurnal (Zhurnal Rossijskogo himicheskogo obshhestva im. D.I. Mendeleeva. 2008; 1(2): 130–135.
  21. Afifi A., Jejzen S. Statisticheskij analiz. Podhod s ispol'zovaniem JeVM. M.: Mir. 1982; 488.