Нажмите на эту строку чтобы перейти к Новостям сайта "Русский врач"

Перейти
на сайт
журнала
"Врач"
Перейти на сайт журнала "Медицинская сестра"
Перейти на сайт журнала "Фармация"
Перейти на сайт журнала "Молекулярная медицина"
Перейти на сайт журнала "Вопросы биологической, медицинской и фармацевтической химии"
Журнал включен в российские и международные библиотечные и реферативные базы данных

ВАК (Россия)
РИНЦ (Россия)
Эко-Вектор (Россия)

DAGHESTAN NATURAL SAMPLES OF THE SEEDS OF CARUM CARVI L. AS SOURCES OF TERPENOIDS

DOI: https://doi.org/10.29296/25877313-2019-12-07
Download full text PDF
Issue: 
12
Year: 
2019

F.A. Vagabova Ph.D. (Eng.), Senior Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of RAS (Makhachkala) Е-mail: fazina@mail.ru A.M. Musaev Head of Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of RAS (Makhachkala) Е-mail: musaev-58@lust.ru A.M. Aliev Senior Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of RAS (Makhachkala); Senior Research Scientist institute of physic, Dagestan Federal Research Center of RAS (Makhachkala) Е-mail: aslan4848@yahoo.com G.K. Radjabov Research Scientist, Laboratory of Phytochemistry and Medical Botany, Mountain Botanical Garden, Dagestan Federal Research Center of RAS (Makhachkala) Е-mail: chem.@mail.ru

The component composition of the essential oil of the fruits of Carum carvi L., collected from the natural populations of Dagestan in 2015 during their full maturation, was studied for the first time. The investigated essential oil obtained from the fruit by the method of hydrodistillation on the device clevenger within 3 hours. The resulting oil had a light yellow color, the output was from 1.35 to 4.88%, depending on the place of growth of raw materi-als. Chromato-mass spectral analysis of the component composition of volatile substances of essential oils revealed 12 characteristic compounds for this type. Each of the chromatographic peaks is identified by a retention index and MS data. The main components of the essential oil of seeds of all the population are carvon (47.55–52.59%) and limonene (43.67–48.02%), making up about 90% of the sum of all components. These compounds have a wide pharmaceutical effect. It should be noted that some valuable components, such as carvacrol, were not found in the essential oils of the fruits of the Daghestani samples of C. carvi, but compounds were found that are not characterized by the samples of essential oils given in the litera-ture. Cluster analysis by the component attribute of C. carvi fruit essential oils showed a strong scatter of cumin seed populations between samples according to geography.

Keywords: 
Сarum carvi L.
essential oil
carvon
limonene
essential oil components
chromatography-mass spectrometry
population

It appears your Web browser is not configured to display PDF files. Download adobe Acrobat или click here to download the PDF file.

References: 
  1. Tamador A.A., Ezeldin M., Masaad A.M., Ishak С.Y, Alnoor R., Alnoor W.A., Mansour Sh., Hassan Z., Almahal M. Evaluation of essential oil, seed extracts, of Carum carvi L. // Elixir Org. Chem. 2016. V. 8. P. 2518–2522.
  2. Acimovic M.G., Oljaca S.I., Tesevic V.V., Todosijevic M.M.. Evalution of caraway essential oil different production areas of Serbia // Hort. Sci. 2014. V. 41. № 3. P. 122–130.
  3. Azimova Sh.S., Glushenkova A.I. Lipids, lipophilic components and essential oils from plant sources // London, 2012. P. 17–18. doi:10.1007/978-0-85729-323-7.
  4. Ushakova I.T., Xarchenko V.A., Bespalko L.V., Shevchenko Yu.P., Kurbakov U.L. Tmin oby`knovenny`j (Carum carvi L.) // Ovoshhi Rossii. 2016. № 4. P. 21–24. https://doi.org/10.18619/2072-9146-2016-4-21-24.
  5. Laribi B.; Kouki K.; Mougou A.; Marzouk B. Fatty acid and essential oil composition of 3 Tunisian caraway (Carum carvi L.) seed ecotypes // J. Sci. Food Agric. 2010. V. 90. P. 391–396.
  6. Krotova I.V., Efremov A.A. Vozmozhnosti racional`nogo ispol`zovaniya e`firomaslichny`x rastenij // Ximiya rastitel`nogo sy`r`ya. 2002. № 3. P. 29–33.
  7. Villarini M., Fatigoni C., Cerbone B., Dominici L., Moretti M., Pagiotti R.J. In vitro testing of a laxative herbal food supplement for genotoxic and antigenotoxic properties // Journal of Medicinal Plants Research. 2011. V. 5. № 12. P. 2533–2539.
  8. Samojlik I., Lakic N., Mimica-Dukic N., Dakovic-Svajcer K., Bozin B. Antioxidant and hepatoprotective potential of essential oils of coriander (Coriandrum sativum L.) and carawa(Carum carvi L.) (Apiaceae) // J. Agric. Food Chem. 2010. V. 58. № 15. P. 8848-8853. doi: 10.1021/jf101645n.
  9. Seidler-Lozykowska K., Baranska M., Baranski R., Krol D. Raman analysis of caraway (Carum carvi L.) single fruits. Evaluation of essential oil content and its composition // J. Agric. Food Chem. 2010. V. 58. P. 5271–5275.
  10. Simic A., Rancic A., Sokovic M.D., Ristic M., Grujic-Jovanovic S., Vukojevic J., Marin P.D. Essential oil composition of Cymbopogon winterianus and Carum carvi and their antimicrobial activities // Pharm. Biol. (NY, USA). 2008. V. 46. P. 437–441.
  11. Iacobellis N.S., Lo Cantore P., Capasso F., Senatore F. Antibacterial activity of Cuminum cyminum L. and Carum carvi L. essential oils // J. Agric. Food Chem. 2005. V. 53. P. 57–61.
  12. Rauha J.P., Remes S., Herinonen W., Hopia M., Kgjala T., Pitinlaja K., Vaorela H., Vaorela P.. Antimicrobial effects of finished plant extract containing flavanoids and other phenolic compounds // Int. J. Food Microbiol. 2000. V. 56. P. 3–12.
  13. Djeridane A., Yousfi M., Nadjemi B., Boutassouna D., Stocher P., Vidal N. Antioxidant activity of some Algerian medicinal plants extracts containing phenolic compounds // Food Chemistry. 2006. V. 97. P. 654–660.
  14. Fang R., Jiang C.H., Wang X.Y, Zhang H.M., Liu Z.L., Zhou L.G., Du S.S., Deng Z. W. Insecticidal activity oil of Carum carvi fruits from China and its main components against two grain storage insects // Molecules. 2010. V. 15. P. 9391–9402. doi: 10.3390/molecules15129391.
  15. Begum J., Bhuiyan M.N.I., Chowdhury J.U., Hoque M.N. Antimicrobial activity of essential oil from seeds of Carum carvi and its composition. Bangladesh // J. Microbiol. 2008. V. 25. P. 85–89. doi:10.3329/bjm.v25i2.4867.
  16. Islamova F.A., Musaev A.M., Radzhabov G.K., Vagabova F.A., Gusejnova Z.A., Mamalieva M.M. Trendy` izmenchivosti soderzhaniya summarny`x antioksidantov i e`firnogo masla v semenax Sarum carvi L. vdol` vy`sotnogo gradienta v gornom Dagestane // Voprosy` biologicheskoj, medicinskoj i farmacevticheskoj ximii. 2016. № 19(12). P. 19–23.
  17. Samusenko A.L. Izuchenie zavisimosti antioksidantnoj aktivnosti e`firny`x masel koriandra, imbirya, semyan tmina i rozovogo grejpfruta ot koncentracii masla v sisteme metodom kapillyarnoj gazovoj xromatografii // Ximiya rastitel`nogo sy`r`ya. 2014. № 1. S. 221–227. doi:10.14258/Jcprm.1401221.
  18. Almehemdi A.F.A., Stolarska A., Nasralla A.Y. Effect оf sowing dates on volatile oil %, its yield and components of caraway // The Iraqi Journal of Agricultural Sciences. 2011. V. 42. № 2. P. 13–44.
  19. Shishov A.D., Lesovskaya S.G., Ivanov M.G. Larionova S.L. Vliyanie sroka poseva i razlichny`x pochvenny`x na urozhajnost` plodov (semyan) tmina, ix kachestvo i soderzhanie e`firny`x masel // Ucheny`e zapiski ASXiPR NovGU. V. Novgorod. 2001. № 5(1). S. 49–51.
  20. Ivanov M.G. Vozdely`vanie tmina oby`knovennogo v usloviyax Novgorodskoj oblasti // Sovremenny`e problemy` nauki i obrazovaniya. 2012. № 6. URL: http://www.science-education.ru/ru/article/view?id=7551 (дата обращения: 14.05.2019).
  21. Johri R.K. Cuminum cyminum and Carum carvi: An update // Pharmacogn. Rev. 2011. V. 5. № 9. P. 63–72.
  22. Kallio H., Kerrola K., Alhonmaki P. Carvone and limonene in caraway fruits (Carum carvi L.) analyzed by supercritical carbon dioxide extraction-gas chromatography // Journal of Agricultural and Food Chemistry. 1994. V. 42. № 11. P. 2478–2485. doi:10.1021/jf00047a021.
  23. Kuramagomedov M.K., Musaev A.M., Gusejnova Z.A. Xarakter izmenchivosti morfologicheskix priznakov Sarum carvi L. v prirodny`x populyaciyax Dagestana // Vestnik Voronezhskogo gosudarstvennogo universiteta. Seriya: Geografiya. Geoe`kologiya. 2018. № 1. C. 78–83.
  24. Murtazaliev R.A. Konspekt flory` Dagestana / Otv. ped. chl.-kor. RAN R.V. Kamelin. Maxachkala: «E`poxa», 2009. T. III. 304 c.
  25. Gosudarstvennaya Farmakopeya SSSR. Obshhie metody` analiza. Lekarstvennoe rastitel`noe sy`r`e. Izd. 13-e. 2017. http://www.femb.ru/feml.
  26. Vagabova F.A., Aliev A.M., Radzhabov G.K., Musaev A.M. Sravnitel`noe izuchenie komponentnogo sostava e`firnogo masla Artemisia splendens Willd. i Artemisia tschernie¬viana Bess. flory` Dagestana // Voprosy` biologicheskoj, medicinskoj i farmacevticheskoj ximii. 2018. № 21(1). S. 17–24. doi: 10.29296/25877313-2018-01-04.